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MDMA Ecstasy (Methylenedioxymethamphetamine)
QuickScreen™ One-Step Rapid Drug Screen Test (Cassette type)

A Professional, Forensic Diagnostic Test for use in the Specific Qualitative Detection of MDMA (Ecstasy) in Human Urine at a minimum sensitivity cut-off level of 500 ng/ml Established as Standard by the U.S. Department of Health and Human Services, World Health Organization and SAMHSA (NIDA).


For a comprehensive discussion on drug of abuse testing including typical detection time periods see the DRUG TESTING FAQ

The QuickScreen™ One-Step Rapid MDMA (Ecstasy) Test is a rapid, qualitative, competitive binding immunoassay for the specific detection of Methylenedioxymethamphetamine (MDMA) metabolites in urine. The test provides a fast (3 minute) confirmation of the presence of MDMA in the subject sample at a minimum cutoff sensitivity level of 500 ng/ml MDMA. Note: it is recommended that any positive test be confirmed using quantitative methods by a qualified healthcare professional.
Note: This assay provides only a preliminary analytical test result. A more specific alternative chemical method such as high-pressure liquid chromatography (HPLC) or Gas chromatography/mass spectrometry (GC/MS) must be used in order to obtain a confirmed analytical result. For test situations requiring laboratory confirmation by such methods please refer to the QuickScreen Pro At Home Test Kit. Clinical consideration and professional judgment should be applied to all test results, particularly when preliminary positive results are indicated.


Methylenedioxymethamphetamine (Ecstasy) is a designer drug first synthesized in 1913 by a German drug company for the treatment of obesity. Those who take the drug frequently report adverse effects, such as increased muscle tension and sweating. MDMA is not clearly a stimulant, although it has, in common with amphetamine drugs, a capacity to increase blood pressure and heart rate. MDMA does produce some perceptual changes in the form of increased sensitivity to light, difficulty in focusing, and blurred vision in some users. Its mechanism of action is thought to be via release of the neurotransmitter serotonin. MDMA may also release dopamine, although the general opinion is that this is a secondary effect of the drug. The most pervasive effect of MDMA, occurring in almost all people who have taken a reasonable dose of the drug, is to produce a clenching of the jaws. The MDMA Ecstasy Test yields a positive result when Methylenedioxymethamphetamine in urine exceeds 500ng/ml which is the NIDA standard.

The excretion half-life of MDMA metabolized in urine, estimated by different techniques, ranges from two to three days. The QuickScreen™ One-Step Ecstasy Test employs a unique combination of monoclonal antibodies to selectively identify MDMA metabolites in urine with a high degree of sensitivity. The test device is a rapid, visually read screening test that does not require instrumentation and provides a fast indication of recent Ecstasy consumption. For comprehensive information on drug testing including typical half-life or drug detection periods see the Drug Testing FAQ.

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The QuickScreen™ One-Step Rapid MDMA Test technology incorporates a chromatographic absorbent device in which the drug or drug metabolites in the sample compete with a MDMA derivative immobilized on a porous membrane for limited antibody sites. This is the preferred scientific method for qualitative assay. In the assay procedure, urine mixes with labeled antibody-dye conjugate and migrates through test device. When MDMA levels are below 500 ng/ml (the detection cutoff sensitivity of the test) unbound antibody-dye conjugate binds to immobilized antigen conjugate in the Test Zone ("T"), producing a pink-rose colored band that indicates a negative result. Conversely, when MDMA levels are above the detection limit, antibody-dye conjugate binds to the free drug, forming an antigen-antibody-dye complex. The complex competes with immobilized antigen conjugate in the Test Zone, preventing the development of a pink-rose colored band. Regardless of the test result, a color band is produced in the Control Zone ("C") by a non-specific sandwich dye conjugate reaction. This band serves as a built-in quality control by demonstrating antibody recognition, verifying that the reagents are chemically active, and confirming that the test was performed correctly.


QuickScreen™ One-Step MDMA test device and dropper pipette individually sealed in foil pouch with complete instructions.


  1. Collect a urine sample from test subject using a suitable clean container preferably glass.

  2. Refrigerated specimens or other materials should be equilibrated to room temperature before testing.

  3. Open the foil pouch at the notch, remove the test device, and label the device with specimen ID.

  4. Holding the dropper vertically as shown, add 4 drops of urine into the sample well "S" waiting 5 seconds between drops.

  5. Observe migration, or lateral flow of the sample across the entire test panel. Add additional sample drops if migration is not complete.

  6. Positive results may be observed as soon as 3 minutes, depending on the concentration of the MDMA in the tested specimen. To confirm negative results, a complete reaction time of 8 minutes is required. Do not interpret results after 10 minutes.





The development of two lines, a control line and a test line, no matter how faint, in the test result window indicates a negative test screen for the targeted drug or drug metabolite.

The development of only one line, the control line, in the test result window indicates a positive test screen for the targeted drug or drug metabolite

The absence of a control line in the test result window indicates an invalid test result regardless of the presence of a test line in the test result window.

Positive: One (1) pink-rose band appears in the control zone and no band appears in the test zone. A positive result indicates MDMA level is 500 ng/ml or higher in the test urine sample.
Negative: One band appears in the test zone and one band appears in the control zone. A negative result indicates that MDMA level is below the detection sensitivity of 500 ng/ml. IMPORTANT: any line, no matter how faint, appearing in the test area confirms a negative test.
Invalid: If there are no distinct color bands visible in both the test zone and the control zone or if there is a visible band in the test zone but not in the control zone, then the test is invalid. In this instance, re-testing of the specimen is recommended.


The QuickScreen™ One-Step Rapid MDMA Test is now available to professionals and individuals concerned with MDMA consumption or abuse. The test is one-step, fast, self-contained, individually packaged and can be performed any time the targeted drug use or abuse is suspected. The tests come in order units of five (5) individual tests at a cost per single diagnosis/screen of $4.00 for the minimum order unit. For testing situations where sample adulteration is suspect, a Rapid Urine Adulteration test is available.

Test Description/Type Quantity Cost  

QuickScreen MDMA (Ecstasy) Cassette Test

Five (5) Tests



Fifteen (15) Tests



Thirty (30) Tests



One Hundred (100) Tests



Two Hundred Fifty (250) Tests


*If the order buttons are absent or inoperable, please use the pricing overview page to order.

Urine Sample Validity
and Adulteration Test Strips are available:
Adulteration Test

Professional specimen collection containers available separately: Specimen Containers


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